IKP-104 is a microtubule/tubulin inhibitor (IC50 = 1.31 µM). IKP-104 arrests cells in mitosis and the M phase by inhibiting microtubule polymerization and inducing cytoskeletal microtubule depolymerization. IKP-104 inhibits the growth of mouse and human tumor cell lines. IKP-104 exhibits anti-tumor effects in mouse ascites tumors and lung cancer models. IKP-104 is useful in the research of cancers such as leukemia, lung cancer and melanoma[1][2][3][4].
Molecular Weight:
449.90
CAS Number:
[114231-14-0]
Formula:
C26H21ClFNO3
Target:
Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound1
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