Mesothelin (Mesothelial Marker) Antibody, IgG2b, Clone: [MSVA-235M], Mouse, Monoclonal

Produktübersicht

• Artikelname: Mesothelin (Mesothelial Marker) Antibody, IgG2b, Clone: [MSVA-235M], Mouse, Monoclonal
• Artikelnummer: NBT-10232-MSM22-P0
• Hersteller Artikelnummer: 10232-MSM22-P0
• Alternativnummer: NBT-10232-MSM22-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)
• Alternative Synonym: CAK1, Megakaryocyte potentiating factor, Mesothelin, MSLN, SMR, SMRP

Produktbeschreibung

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MSVA-235M]
• Molekulargewicht: 40kDa (Mature form), 69kDa (Precursor)
• Isotyp: IgG2b
• NCBI: 10232
• UniProt: Q13421
• Formulierung: Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Bilder

Mesothelin Mouse Monoclonal Antibody (MSVA-235M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.