Mesothelin (Mesothelial Marker) Antibody, IgG2b, Clone: [MSVA-235M], Mouse, Monoclonal

Product Overview

• Article Name: Mesothelin (Mesothelial Marker) Antibody, IgG2b, Clone: [MSVA-235M], Mouse, Monoclonal
• Biozol Catalog Number: NBT-10232-MSM22-P0
• Supplier Catalog Number: 10232-MSM22-P0
• Alternative Catalog Number: NBT-10232-MSM22-P0-20
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)
• Alternative Names: CAK1, Megakaryocyte potentiating factor, Mesothelin, MSLN, SMR, SMRP

Product Description

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MSVA-235M]
• Molecular Weight: 40kDa (Mature form), 69kDa (Precursor)
• Isotype: IgG2b
• NCBI: 10232
• UniProt: Q13421
• Form: Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Images

Mesothelin Mouse Monoclonal Antibody (MSVA-235M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.