CFL2 / NEM7 Antibody, IgG1, Clone: [CFL2/9963], Mouse, Monoclonal

Produktübersicht

• Artikelname: CFL2 / NEM7 Antibody, IgG1, Clone: [CFL2/9963], Mouse, Monoclonal
• Artikelnummer: NBT-1073-MSM3-P1ABX
• Hersteller Artikelnummer: 1073-MSM3-P1ABX
• Alternativnummer: NBT-1073-MSM3-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa1-166) of human CFL2 protein (exact sequence is proprietary)
• Alternative Synonym: NEM7

Produktbeschreibung

Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [CFL2/9963]
• Molekulargewicht: 19-21kDa
• Isotyp: IgG1
• NCBI: 1073
• UniProt: Q9Y281
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.