Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [FTL/1389], Mouse, Monoclonal

Produktübersicht

• Artikelname: Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [FTL/1389], Mouse, Monoclonal
• Artikelnummer: NBT-2512-MSM4-P1
• Hersteller Artikelnummer: 2512-MSM4-P1
• Alternativnummer: NBT-2512-MSM4-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
• Alternative Synonym: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Produktbeschreibung

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [FTL/1389]
• Molekulargewicht: 19-25kDa
• Isotyp: IgG1
• NCBI: 2512
• UniProt: P02792
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

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