Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [FTL/1389], Mouse, Monoclonal

Product Overview

• Article Name: Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody, IgG1, Clone: [FTL/1389], Mouse, Monoclonal
• Biozol Catalog Number: NBT-2512-MSM4-P1
• Supplier Catalog Number: 2512-MSM4-P1
• Alternative Catalog Number: NBT-2512-MSM4-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
• Alternative Names: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Product Description

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [FTL/1389]
• Molecular Weight: 19-25kDa
• Isotype: IgG1
• NCBI: 2512
• UniProt: P02792
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

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