Recombinant Cytokeratin 7 (Glandular and Transitional Epithelial Marker) Antibody, Clone: [KRT7/8121R], Rabbit, Monoclonal

Artikelnummer: NBT-3855-RBM17-P0
Artikelname: Recombinant Cytokeratin 7 (Glandular and Transitional Epithelial Marker) Antibody, Clone: [KRT7/8121R], Rabbit, Monoclonal
Artikelnummer: NBT-3855-RBM17-P0
Hersteller Artikelnummer: 3855-RBM17-P0
Alternativnummer: NBT-3855-RBM17-P0-20,NBT-3855-RBM17-P0-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant fragment (around aa1-200) of human KRT7 protein (exact sequence is proprietary)
Alternative Synonym: CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7
Cytokeratin 7 in humans is a protein encoded by the KRT7 gene. It is always as a keratin pair with Cytokeratin 19. Cytokeratin 7 is expressed on most ductal and glandular epithelium including lung, breast, bladder and female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. In tumor tissues, its expression is absent in colon cancer, prostate cancer and squamous carcinomas. Cytokeratin 7 is often used in concert with Cytokeratin 20 and CDX-2 to aid in distinguishing ovarian, pulmonary and breast carcinomas (CK7+) from colon carcinomas (CK7-).
Klonalität: Monoclonal
Klon-Bezeichnung: [KRT7/8121R]
Molekulargewicht: 55kDa
NCBI: 3855
UniProt: P08729
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio
Formalin-fixed, paraffin-embedded human lung carcinoma stained with Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody (KRT7/8121R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human placenta stained with Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody (KRT7/8121R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.