Cytokeratin 5/6 (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody, IgG1, Clone: [KRT5.6/4866], Mouse, Monoclonal

Produktübersicht

• Artikelname: Cytokeratin 5/6 (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody, IgG1, Clone: [KRT5.6/4866], Mouse, Monoclonal
• Artikelnummer: NBT-MSM46-4866-P1
• Hersteller Artikelnummer: MSM46-4866-P1
• Alternativnummer: NBT-MSM46-4866-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human KRT5 protein
• Alternative Synonym: CK5, Keratin-5, KRT5, Cytoskeletal 6A, KRT6A

Produktbeschreibung

It recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma. It does not react with pulmonary adenocarcinoma.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [KRT5.6/4866]
• Molekulargewicht: 58kDa (KRT5), 56kDa (KRT6A)
• Isotyp: IgG1
• NCBI: 3852
• UniProt: P13647
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/4866).

Formalin-fixed, paraffin-embedded human prostate stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/4866).