Cytokeratin 5/6 (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody, IgG1, Clone: [KRT5.6/4866], Mouse, Monoclonal

Product Overview

• Article Name: Cytokeratin 5/6 (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody, IgG1, Clone: [KRT5.6/4866], Mouse, Monoclonal
• Biozol Catalog Number: NBT-MSM46-4866-P1
• Supplier Catalog Number: MSM46-4866-P1
• Alternative Catalog Number: NBT-MSM46-4866-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant full-length human KRT5 protein
• Alternative Names: CK5, Keratin-5, KRT5, Cytoskeletal 6A, KRT6A

Product Description

It recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma. It does not react with pulmonary adenocarcinoma.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [KRT5.6/4866]
• Molecular Weight: 58kDa (KRT5), 56kDa (KRT6A)
• Isotype: IgG1
• NCBI: 3852
• UniProt: P13647
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Images

Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/4866).

Formalin-fixed, paraffin-embedded human prostate stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/4866).