MeCP2 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: MeCP2 Antibody, Rabbit, Polyclonal
• Artikelnummer: NSJ-F41828-0.08ML
• Hersteller Artikelnummer: F41828-0.08ML
• Alternativnummer: NSJ-F41828-0.08ML
• Hersteller: NSJ Bioreagents
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, FACS, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.

Produktbeschreibung

MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]

Produkteigenschaften

• Klonalität: Polyclonal
• UniProt: P51608
• Reinheit: Antigen affinity
• Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
• Anwendungsbeschreibung: Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.