MeCP2 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: MeCP2 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: NSJ-F41828-0.08ML
• Supplier Catalog Number: F41828-0.08ML
• Alternative Catalog Number: NSJ-F41828-0.08ML
• Manufacturer: NSJ Bioreagents
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, FACS, IHC, WB
• Species Reactivity: Human
• Immunogen: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.

Product Description

MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]

Product Properties

• Clonality: Polyclonal
• UniProt: P51608
• Purity: Antigen affinity
• Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
• Application Notes: Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.