DR1 Antibody (Down-regulator of transcription 1), Rabbit, Polyclonal
Artikelnummer:
NSJ-F45943-0.4ML
Hersteller Artikelnummer:
F45943-0.4ML
Alternativnummer:
NSJ-F45943-0.4ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
A portion of amino acids 83-112 from the human protein was used as the immunogen for this DR1 antibody.
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
