MGEA5 Antibody / OGA / O-GlcNAcase, Rabbit, Polyclonal

Produktübersicht

• Artikelname: MGEA5 Antibody / OGA / O-GlcNAcase, Rabbit, Polyclonal
• Artikelnummer: NSJ-F54180-0.2ML
• Hersteller Artikelnummer: F54180-0.2ML
• Alternativnummer: NSJ-F54180-0.2ML
• Hersteller: NSJ Bioreagents
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: A portion of amino acids 236-269 from human MGEA5 was used as the immunogen for the MGEA5 antibody.

Produktbeschreibung

Isoform 1 (Cytoplasmic): Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714).Isoform 3 (Nuclear): Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1. [UniProt]

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Isotyp: Rabbit Ig
• UniProt: O60502
• Puffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reinheit: Antigen affinity
• Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Target-Kategorie: MGEA5
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot: 1:1000-1:2000
• Anwendungsbeschreibung: The stated application concentrations are suggested starting points. Titration of the MGEA5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

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