Tau-441 (P301S) protein

Artikelnummer: ROC-009-001-U01S
Artikelname: Tau-441 (P301S) protein
Artikelnummer: ROC-009-001-U01S
Hersteller Artikelnummer: 009-001-U01S
Alternativnummer: ROC-009-001-U01S
Hersteller: Rockland Immunochemicals
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: Tau-F, (N2R4), Tau-4, MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Microtubule-associated protein tau
Konzentration: 0.2ug/ul
NCBI: 10636
UniProt: P10636
Puffer: See application note.
Formulierung: Liquid (sterile filtered)
Application Verdünnung: WB: User Optimized
Anwendungsbeschreibung: Tau-441 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Tau-441 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~63kDa on specific lysates or tissues. Specific condit
Sup35NM seeds P301S mutant tau aggregation in vitro. A-C, Transmission electron microscope images of negatively stained preparations of human 2N4R P301S mutant tau monomer aggregates, formed under low heparin conditions (A), and after addition of -5TyrSup35NM monomers (B), or Sup35NM seeds (C), at days 0, 3, and 16. Note the occurrence of corkscrew-shaped tau fibrils at days 3 and 16 upon seeding with Sup35NM fibrils (arrows, C). Scale bar for all images: 500nm, for all magnified insets: 100nm. Fig 1. PMID: 35142027.