Tau-441 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Tau-441 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~63kDa on specific lysates or tissues. Specific condit
Sup35NM seeds P301S mutant tau aggregation in vitro. A-C, Transmission electron microscope images of negatively stained preparations of human 2N4R P301S mutant tau monomer aggregates, formed under low heparin conditions (A), and after addition of -5TyrSup35NM monomers (B), or Sup35NM seeds (C), at days 0, 3, and 16. Note the occurrence of corkscrew-shaped tau fibrils at days 3 and 16 upon seeding with Sup35NM fibrils (arrows, C). Scale bar for all images: 500nm, for all magnified insets: 100nm. Fig 1. PMID: 35142027.
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