Tau-441 (P301S) protein

Product Overview

• Article Name: Tau-441 (P301S) protein
• Biozol Catalog Number: ROC-009-001-U01S
• Supplier Catalog Number: 009-001-U01S
• Alternative Catalog Number: ROC-009-001-U01S
• Manufacturer: Rockland Immunochemicals
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Tau-F, (N2R4), Tau-4, MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Microtubule-associated protein tau

Product Properties

• Concentration: 0.2ug/ul
• NCBI: 10636
• UniProt: P10636
• Buffer: See application note.
• Form: Liquid (sterile filtered)

Application Notes

• Application Dilute: WB: User Optimized
• Application Notes: Tau-441 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Tau-441 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~63kDa on specific lysates or tissues. Specific condit

Images

Sup35NM seeds P301S mutant tau aggregation in vitro. A-C, Transmission electron microscope images of negatively stained preparations of human 2N4R P301S mutant tau monomer aggregates, formed under low heparin conditions (A), and after addition of -5TyrSup35NM monomers (B), or Sup35NM seeds (C), at days 0, 3, and 16. Note the occurrence of corkscrew-shaped tau fibrils at days 3 and 16 upon seeding with Sup35NM fibrils (arrows, C). Scale bar for all images: 500nm, for all magnified insets: 100nm. Fig 1. PMID: 35142027.