Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq), IgG1

Produktübersicht

• Artikelname: Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq), IgG1
• Artikelnummer: SYB-CHB256
• Hersteller Artikelnummer: CHB256
• Alternativnummer: SYB-CHB256-100UG,SYB-CHB256-1MG
• Hersteller: Sanyou Bio
• Kategorie: Antikörper
• Applikation: ELISA, FA, FACS, Kinetics
• Spezies Reaktivität: Human
• Alternative Synonym: RG7596, DCDS4501A, huMA79b.v28

Produktbeschreibung

Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.

Produkteigenschaften

• Konzentration: 1mg/ml
• Molekulargewicht: 150.53 kDa
• Isotyp: IgG1
• NCBI: 40259
• UniProt: P40259
• Puffer: 25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
• Reinheit: >90%
• Formulierung: Lyophilize
• Target-Kategorie: CD79b