Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq), IgG1

Product Overview

• Article Name: Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq), IgG1
• Biozol Catalog Number: SYB-CHB256
• Supplier Catalog Number: CHB256
• Alternative Catalog Number: SYB-CHB256-100UG,SYB-CHB256-1MG
• Manufacturer: Sanyou Bio
• Category: Antikörper
• Application: ELISA, FA, FACS, Kinetics
• Species Reactivity: Human
• Alternative Names: RG7596, DCDS4501A, huMA79b.v28

Product Description

Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.

Product Properties

• Concentration: 1mg/ml
• Molecular Weight: 150.53 kDa
• Isotype: IgG1
• NCBI: 40259
• UniProt: P40259
• Buffer: 25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
• Purity: >90%
• Form: Lyophilize
• Target: CD79b