GNE-987, CAS [[2417371-71-0]]

Produktübersicht

• Artikelname: GNE-987, CAS [[2417371-71-0]]
• Artikelnummer: TGM-T11441
• Hersteller Artikelnummer: T11441
• Alternativnummer: TGM-T11441-1MG,TGM-T11441-5MG,TGM-T11441-10MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GNE987 , GNE 987

Produktbeschreibung

GNE-987 is a highly active chimeric BET degrader that binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low-nanomolar affinity and induces exceptionally potent BRD4 degradation in cells, achieving picomolar DC50 values in EOL-1 acute myeloid leukemia cells, thereby serving as a powerful chemical biology tool for dissecting BET-dependent transcriptional regulation.

Produkteigenschaften

• Molekulargewicht: 1096.31
• CAS Nummer: [2417371-71-0]
• Formel: C56H67F2N9O8S2
• Target-Kategorie: Epigenetic Reader Domain

Bilder

T11441

T11441