GNE-987, CAS [[2417371-71-0]]

Product Overview

• Article Name: GNE-987, CAS [[2417371-71-0]]
• Biozol Catalog Number: TGM-T11441
• Supplier Catalog Number: T11441
• Alternative Catalog Number: TGM-T11441-1MG,TGM-T11441-5MG,TGM-T11441-10MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: GNE987 , GNE 987

Product Description

GNE-987 is a highly active chimeric BET degrader that binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low-nanomolar affinity and induces exceptionally potent BRD4 degradation in cells, achieving picomolar DC50 values in EOL-1 acute myeloid leukemia cells, thereby serving as a powerful chemical biology tool for dissecting BET-dependent transcriptional regulation.

Product Properties

• Molecular Weight: 1096.31
• CAS Number: [2417371-71-0]
• Formula: C56H67F2N9O8S2
• Target: Epigenetic Reader Domain

Images

T11441

T11441