MRTX-1257, CAS [[2206736-04-9]]

Produktübersicht

• Artikelname: MRTX-1257, CAS [[2206736-04-9]]
• Artikelnummer: TGM-T16143
• Hersteller Artikelnummer: T16143
• Alternativnummer: TGM-T16143-1MLX10MM(INDMSO),TGM-T16143-1MG,TGM-T16143-2MG,TGM-T16143-5MG,TGM-T16143-10MG,TGM-T16143-25MG,TGM-T16143-50MG,TGM-T16143-100MG,TGM-T16143-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C with an IC50 of 900 pM for KRAS-dependent ERK phosphorylation in H358 cells. MRTX-1257 demonstrated 31% bioavailability in the mouse, with free fraction exposures well above cellular potency, and 77% target engagement in a PK/PD experiment.

Produkteigenschaften

• Molekulargewicht: 565.71
• Reinheit: 96.59%
• CAS Nummer: [2206736-04-9]
• Formel: C33H39N7O2
• Target-Kategorie: Ras|||Kras

Bilder

T16143