PIN1 inhibitor API-1, CAS [[680622-70-2]]

Produktübersicht

• Artikelname: PIN1 inhibitor API-1, CAS [[680622-70-2]]
• Artikelnummer: TGM-T16538
• Hersteller Artikelnummer: T16538
• Alternativnummer: TGM-T16538-1MLX10MM(INDMSO),TGM-T16538-1MG,TGM-T16538-5MG,TGM-T16538-10MG,TGM-T16538-25MG,TGM-T16538-50MG,TGM-T16538-100MG,TGM-T16538-200MG,TGM-T16538-500MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM) that retains the active conformation of pXPO5, restoring its ability to transport pre-miRNAs from the nucleus to the cytoplasm, thereby up-regulating anticancer miRNA biogenesis to suppress hepatocellular carcinoma development both in vitro and in vivo. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase domain, effectively inhibiting Pin1 cis-trans isomerizing activity.

Produkteigenschaften

• Molekulargewicht: 366.3
• Reinheit: 95.52%
• CAS Nummer: [680622-70-2]
• Formel: C15H13F3N6O2
• Target-Kategorie: MicroRNA

Bilder

T16538