PIN1 inhibitor API-1, CAS [[680622-70-2]]

Product Overview

• Article Name: PIN1 inhibitor API-1, CAS [[680622-70-2]]
• Biozol Catalog Number: TGM-T16538
• Supplier Catalog Number: T16538
• Alternative Catalog Number: TGM-T16538-1MLX10MM(INDMSO),TGM-T16538-1MG,TGM-T16538-5MG,TGM-T16538-10MG,TGM-T16538-25MG,TGM-T16538-50MG,TGM-T16538-100MG,TGM-T16538-200MG,TGM-T16538-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM) that retains the active conformation of pXPO5, restoring its ability to transport pre-miRNAs from the nucleus to the cytoplasm, thereby up-regulating anticancer miRNA biogenesis to suppress hepatocellular carcinoma development both in vitro and in vivo. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase domain, effectively inhibiting Pin1 cis-trans isomerizing activity.

Product Properties

• Molecular Weight: 366.3
• Purity: 95.52%
• CAS Number: [680622-70-2]
• Formula: C15H13F3N6O2
• Target: MicroRNA

Images

T16538