Momelotinib, CAS [[1056634-68-4]]

Artikelnummer: TGM-T1849
Artikelname: Momelotinib, CAS [[1056634-68-4]]
Artikelnummer: TGM-T1849
Hersteller Artikelnummer: T1849
Alternativnummer: TGM-T1849-1MLX10MM(INDMSO),TGM-T1849-1MG,TGM-T1849-2MG,TGM-T1849-5MG,TGM-T1849-10MG,TGM-T1849-25MG,TGM-T1849-50MG,TGM-T1849-100MG,TGM-T1849-200MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: LM-1149 , CYT11387 , CYT387
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.
Molekulargewicht: 414.46
Reinheit: 97.07%
CAS Nummer: [1056634-68-4]
Formel: C23H22N6O2
Target-Kategorie: Apoptosis|||JAK|||Autophagy
T1849