Momelotinib, CAS [[1056634-68-4]]
Artikelnummer:
TGM-T1849
- Bilder (1)
| Artikelname: | Momelotinib, CAS [[1056634-68-4]] |
| Artikelnummer: | TGM-T1849 |
| Hersteller Artikelnummer: | T1849 |
| Alternativnummer: | TGM-T1849-1MLX10MM(INDMSO),TGM-T1849-1MG,TGM-T1849-2MG,TGM-T1849-5MG,TGM-T1849-10MG,TGM-T1849-25MG,TGM-T1849-50MG,TGM-T1849-100MG,TGM-T1849-200MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | LM-1149 , CYT11387 , CYT387 |
| Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. |
| Molekulargewicht: | 414.46 |
| Reinheit: | 97.07% |
| CAS Nummer: | [1056634-68-4] |
| Formel: | C23H22N6O2 |
| Target-Kategorie: | Apoptosis|||JAK|||Autophagy |

