KAI-11101, CAS [[3099935-02-8]]

Artikelnummer: TGM-T204384
Artikelname: KAI-11101, CAS [[3099935-02-8]]
Artikelnummer: TGM-T204384
Hersteller Artikelnummer: T204384
Alternativnummer: TGM-T204384-25MG, TGM-T204384-50MG, TGM-T204384-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
KAI-11101 is an inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with a Ki of 0.7 nM. It effectively suppresses paclitaxel-induced cJun phosphorylation (IC50=95 nM), thereby inhibiting the activation of the MAPK pathway. KAI-11101 exhibits blood-brain barrier permeability, allowing for further exploration of its neuroprotective properties.
Molekulargewicht: 469.433
CAS Nummer: [3099935-02-8]
Formel: C21H23F4N5O3
Target-Kategorie: MAP3K|||p38 MAPK|||MAPK
T204384