ChREBPalpha/14-3-3 regulator-1 (Compound 43) is a selective molecular glue that stabilizes the interaction between carbohydrate response element-binding protein (ChREBP) and 14-3-3 proteins, with an EC50 of 3.8 µM. It effectively safeguards beta cells from glucolipotoxicity, preserving cell function and making it relevant for type 2 diabetes research.
Molekulargewicht:
389.263
Formel:
C16H15F3NO5P
Target-Kategorie:
Molecular Glues
T204507
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
