ER degrader 10, CAS [[3035311-43-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: ER degrader 10, CAS [[3035311-43-1]] Preis auf Anfrage
• Artikelnummer: TGM-T204775
• Hersteller Artikelnummer: T204775
• Alternativnummer: TGM-T204775-10MG,TGM-T204775-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 µM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.

Produkteigenschaften

• Molekulargewicht: 497.597
• CAS Nummer: [3035311-43-1]
• Formel: C28H29F2NO3S
• Target-Kategorie: Potassium Channel|||Estrogen Receptor/ERR

Bilder

T204775