ER degrader 10, CAS [[3035311-43-1]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T204775
Supplier Catalog Number:
T204775
Alternative Catalog Number:
TGM-T204775-10MG,TGM-T204775-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 µM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.
Molecular Weight:
497.597
CAS Number:
[3035311-43-1]
Formula:
C28H29F2NO3S
Target:
Potassium Channel|||Estrogen Receptor/ERR
T204775
* VAT and and shipping costs not included. Errors and price changes excepted
