GJG057 is a highly efficient and selective Leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 44 nM in human whole blood LTC4 release assays and oral activity. It demonstrates anti-inflammatory efficacy in a mouse asthma exacerbation model and can be used for the treatment of allergic inflammation.
Molekulargewicht:
456.41
Reinheit:
99.80%
CAS Nummer:
[2761767-18-2]
Formel:
C21H21F5N4O2
Target-Kategorie:
Glutathione Peroxidase|||GST
T205247
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