GJG057 is a highly efficient and selective Leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 44 nM in human whole blood LTC4 release assays and oral activity. It demonstrates anti-inflammatory efficacy in a mouse asthma exacerbation model and can be used for the treatment of allergic inflammation.
Molecular Weight:
456.41
Purity:
99.80%
CAS Number:
[2761767-18-2]
Formula:
C21H21F5N4O2
Target:
Glutathione Peroxidase|||GST
T205247
* VAT and and shipping costs not included. Errors and price changes excepted
