AChE-IN-81 (compound 22) is a reversible, selective inhibitor of AChE with an 80.0% inhibition rate and an IC50 of 3.7 µM. It binds to AChE with an affinity (Kd) of 5.37 µM. AChE-IN-81 effectively reduces apoptosis in zebrafish brain cells and shows potential neuroprotective activity in an H2O2-induced SH-SY5Y cell damage model.
Molekulargewicht:
628.28
Formel:
C37H54ClNO5
Target-Kategorie:
Cholinesterase (ChE)|||Apoptosis
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
