AChE-IN-81 (compound 22) is a reversible, selective inhibitor of AChE with an 80.0% inhibition rate and an IC50 of 3.7 µM. It binds to AChE with an affinity (Kd) of 5.37 µM. AChE-IN-81 effectively reduces apoptosis in zebrafish brain cells and shows potential neuroprotective activity in an H2O2-induced SH-SY5Y cell damage model.
Molecular Weight:
628.28
Formula:
C37H54ClNO5
Target:
Cholinesterase (ChE)|||Apoptosis
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