Semaxinib, CAS [[204005-46-9]]
Artikelnummer:
TGM-T2064
- Bilder (1)
| Artikelname: | Semaxinib, CAS [[204005-46-9]] |
| Artikelnummer: | TGM-T2064 |
| Hersteller Artikelnummer: | T2064 |
| Alternativnummer: | TGM-T2064-1MLX10MM(INDMSO),TGM-T2064-5MG,TGM-T2064-10MG,TGM-T2064-25MG,TGM-T2064-50MG,TGM-T2064-100MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | SU5416 |
| Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 µM), exhibiting a 20-fold greater selectivity for VEGFR2 over PDGFRbeta, with no activity against InsR, EGFR, and FGFR. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting VEGF-stimulated endothelial cell migration and proliferation, thereby reducing tumor microvasculature. |
| Molekulargewicht: | 238.28 |
| Reinheit: | 99.15% |
| CAS Nummer: | [204005-46-9] |
| Formel: | C15H14N2O |
| Target-Kategorie: | VEGFR |

