Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage
• Artikelnummer: TGM-T206652
• Hersteller Artikelnummer: T206652
• Alternativnummer: TGM-T206652-10MG,TGM-T206652-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: CHNQD-01228

Produktbeschreibung

Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins with an IC50 value of 0.22 µM for T24 cell proliferation. It also suppresses T24 cell migration and colony formation in a dose-dependent manner, induces G1 phase arrest, and triggers apoptosis. By targeting BMX proteins, it inhibits the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, while also inhibiting Arf1 proteins to eliminate bladder cancer stem cells and activate antitumor immunity, thus exhibiting anticancer activity. Brefeldin A 4-O-nicotinate is applicable in research related to bladder cancer.

Produkteigenschaften

• Molekulargewicht: 385.453
• CAS Nummer: [3035018-34-6]
• Formel: C22H27NO5
• Target-Kategorie: BTK|||GTPase

Bilder

T206652