Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage

Product Overview

• Article Name: Brefeldin A 4-O-nicotinate, CAS [[3035018-34-6]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206652
• Supplier Catalog Number: T206652
• Alternative Catalog Number: TGM-T206652-10MG,TGM-T206652-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: CHNQD-01228

Product Description

Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins with an IC50 value of 0.22 µM for T24 cell proliferation. It also suppresses T24 cell migration and colony formation in a dose-dependent manner, induces G1 phase arrest, and triggers apoptosis. By targeting BMX proteins, it inhibits the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, while also inhibiting Arf1 proteins to eliminate bladder cancer stem cells and activate antitumor immunity, thus exhibiting anticancer activity. Brefeldin A 4-O-nicotinate is applicable in research related to bladder cancer.

Product Properties

• Molecular Weight: 385.453
• CAS Number: [3035018-34-6]
• Formula: C22H27NO5
• Target: BTK|||GTPase

Images

T206652