HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. It effectively induces the degradation of PD-L1 via a cathepsin B-mediated lysosomal pathway, demonstrating the ability to inhibit tumor cell proliferation, migration, and invasion. HDAC3-IN-7 holds potential for cancer research.
Formel:
C25H37N5O4S
Target-Kategorie:
PD-1/PD-L1|||HDAC
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
