CDK12-IN-8, CAS [[2928619-86-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: CDK12-IN-8, CAS [[2928619-86-5]] Preis auf Anfrage
• Artikelnummer: TGM-T207456
• Hersteller Artikelnummer: T207456
• Alternativnummer: TGM-T207456-10MG,TGM-T207456-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

CDK12-IN-8 (Compound Cpd143) is an orally active, highly selective inhibitor of cyclin-dependent kinase 12 (CDK12). It blocks the phosphorylation of serine 2 in the C-terminal domain (CTD) of RNA polymerase II, thereby interfering with gene transcription elongation and DNA damage repair pathways. CDK12-IN-8 holds potential for research in cancers with high CDK12 expression, such as small cell lung cancer and triple-negative breast cancer.

Produkteigenschaften

• Molekulargewicht: 459.42
• CAS Nummer: [2928619-86-5]
• Formel: C21H20F3N7O2
• Target-Kategorie: CDK

Bilder

T207456