CDK12-IN-8, CAS [[2928619-86-5]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T207456
Supplier Catalog Number:
T207456
Alternative Catalog Number:
TGM-T207456-10MG,TGM-T207456-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
CDK12-IN-8 (Compound Cpd143) is an orally active, highly selective inhibitor of cyclin-dependent kinase 12 (CDK12). It blocks the phosphorylation of serine 2 in the C-terminal domain (CTD) of RNA polymerase II, thereby interfering with gene transcription elongation and DNA damage repair pathways. CDK12-IN-8 holds potential for research in cancers with high CDK12 expression, such as small cell lung cancer and triple-negative breast cancer.
Molecular Weight:
459.42
CAS Number:
[2928619-86-5]
Formula:
C21H20F3N7O2
Target:
CDK
T207456
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