CDK12-IN-8, CAS [[2928619-86-5]] Preis auf Anfrage

Catalog Number: TGM-T207456
Article Name: CDK12-IN-8, CAS [[2928619-86-5]] Preis auf Anfrage
Biozol Catalog Number: TGM-T207456
Supplier Catalog Number: T207456
Alternative Catalog Number: TGM-T207456-10MG,TGM-T207456-50MG
Manufacturer: TargetMol
Category: Biochemikalien
CDK12-IN-8 (Compound Cpd143) is an orally active, highly selective inhibitor of cyclin-dependent kinase 12 (CDK12). It blocks the phosphorylation of serine 2 in the C-terminal domain (CTD) of RNA polymerase II, thereby interfering with gene transcription elongation and DNA damage repair pathways. CDK12-IN-8 holds potential for research in cancers with high CDK12 expression, such as small cell lung cancer and triple-negative breast cancer.
Molecular Weight: 459.42
CAS Number: [2928619-86-5]
Formula: C21H20F3N7O2
Target: CDK
T207456