PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage
• Artikelnummer: TGM-T207578
• Hersteller Artikelnummer: T207578
• Alternativnummer: TGM-T207578-10MG,TGM-T207578-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PDEdelta/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) with a dissociation constant (KD) of 0.410 nM and nicotinamide phosphoribosyltransferase (NAMPT) with an inhibitory concentration (IC50) of 2.21 nM. It disrupts KRAS-related signaling by inhibiting NAMPTs role in the synthesis of nicotinamide adenine dinucleotide (NAD+), consequently inducing apoptosis in pancreatic cancer cells with KRAS mutations. This compound holds potential for research in KRAS-mutant pancreatic cancer.

Produkteigenschaften

• Molekulargewicht: 494.61
• CAS Nummer: [2976498-55-0]
• Formel: C26H30N4O4S
• Target-Kategorie: NAMPT|||Apoptosis|||Ras|||PDE|||Kras

Bilder

T207578