PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T207578
Supplier Catalog Number:
T207578
Alternative Catalog Number:
TGM-T207578-10MG,TGM-T207578-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
PDEdelta/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) with a dissociation constant (KD) of 0.410 nM and nicotinamide phosphoribosyltransferase (NAMPT) with an inhibitory concentration (IC50) of 2.21 nM. It disrupts KRAS-related signaling by inhibiting NAMPTs role in the synthesis of nicotinamide adenine dinucleotide (NAD+), consequently inducing apoptosis in pancreatic cancer cells with KRAS mutations. This compound holds potential for research in KRAS-mutant pancreatic cancer.
Molecular Weight:
494.61
CAS Number:
[2976498-55-0]
Formula:
C26H30N4O4S
Target:
NAMPT|||Apoptosis|||Ras|||PDE|||Kras
T207578
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