N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride, CAS [[4238-41-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride, CAS [[4238-41-9]] Preis auf Anfrage
• Artikelnummer: TGM-T210015
• Hersteller Artikelnummer: T210015
• Alternativnummer: TGM-T210015-10MG,TGM-T210015-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: TLCK hydrochloride

Produktbeschreibung

N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible serine protease inhibitor that functions by alkylating the histidine residue at the active site, thus inhibiting trypsin and trypsin-like proteases. It effectively inhibits caspase-3, caspase-6, and caspase-7 with IC50 values of 12.0, 54.5, and 19.3 µM, respectively. Additionally, N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride induces apoptosis in HL-60 cells and prevents the reduction of mitochondrial transmembrane potential during the apoptosis process.

Produkteigenschaften

• Molekulargewicht: 369.31
• CAS Nummer: [4238-41-9]
• Formel: C14H22Cl2N2O3S
• Target-Kategorie: Serine Protease|||Caspase

Bilder

T210015