N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride, CAS [[4238-41-9]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T210015
Supplier Catalog Number:
T210015
Alternative Catalog Number:
TGM-T210015-10MG,TGM-T210015-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
TLCK hydrochloride
N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible serine protease inhibitor that functions by alkylating the histidine residue at the active site, thus inhibiting trypsin and trypsin-like proteases. It effectively inhibits caspase-3, caspase-6, and caspase-7 with IC50 values of 12.0, 54.5, and 19.3 µM, respectively. Additionally, N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride induces apoptosis in HL-60 cells and prevents the reduction of mitochondrial transmembrane potential during the apoptosis process.
Molecular Weight:
369.31
CAS Number:
[4238-41-9]
Formula:
C14H22Cl2N2O3S
Target:
Serine Protease|||Caspase
T210015
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