HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage
• Artikelnummer: TGM-T210266
• Hersteller Artikelnummer: T210266
• Alternativnummer: TGM-T210266-10MG,TGM-T210266-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

HDAC6-IN-45 (Compound 15) is a selective inhibitor of HDAC6, with an IC50 of 15.2 nM. It exerts neurotrophic effects by upregulating GAP43 and Beta-3 Tubulin markers. Additionally, HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, and inhibits apoptosis in PC12 cells. In zebrafish models of Alzheimers disease, it demonstrates neuroprotective properties. Moreover, HDAC6-IN-45 exhibits antioxidant activity and has favorable blood-brain barrier (BBB) permeability.

Produkteigenschaften

• Molekulargewicht: 393.45
• CAS Nummer: [3048532-05-1]
• Formel: C23H24FN3O2
• Target-Kategorie: HDAC|||Nrf2|||Reactive Oxygen Species|||Apoptosis

Bilder

T210266