HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage

Product Overview

• Article Name: HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T210266
• Supplier Catalog Number: T210266
• Alternative Catalog Number: TGM-T210266-10MG,TGM-T210266-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

HDAC6-IN-45 (Compound 15) is a selective inhibitor of HDAC6, with an IC50 of 15.2 nM. It exerts neurotrophic effects by upregulating GAP43 and Beta-3 Tubulin markers. Additionally, HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, and inhibits apoptosis in PC12 cells. In zebrafish models of Alzheimers disease, it demonstrates neuroprotective properties. Moreover, HDAC6-IN-45 exhibits antioxidant activity and has favorable blood-brain barrier (BBB) permeability.

Product Properties

• Molecular Weight: 393.45
• CAS Number: [3048532-05-1]
• Formula: C23H24FN3O2
• Target: HDAC|||Nrf2|||Reactive Oxygen Species|||Apoptosis

Images

T210266