RUNX1/ETO-IN-1, CAS [[923865-06-9]] Preis auf Anfrage
Artikelnummer:
TGM-T210892
Hersteller Artikelnummer:
T210892
Alternativnummer:
TGM-T210892-10MG,TGM-T210892-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
RUNX1/ETO-IN-1 is an inhibitor targeting the oncogenic fusion protein RUNX1-ETO, specifically affecting the NHR2 oligomerization domain. It binds directly to NHR2 (KD,app = 39 µM). By inducing apoptosis and promoting differentiation, RUNX1/ETO-IN-1 exhibits antileukemic activity in RUNX1/ETO translocation acute myeloid leukemia (AML) cells. Its near-neutral charge under physiological pH conditions grants it excellent cell membrane permeability.
Molekulargewicht:
399.51
CAS Nummer:
[923865-06-9]
Formel:
C21H25N3O3S
Target-Kategorie:
Apoptosis|||Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten