RUNX1/ETO-IN-1, CAS [[923865-06-9]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T210892
Supplier Catalog Number:
T210892
Alternative Catalog Number:
TGM-T210892-10MG,TGM-T210892-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
RUNX1/ETO-IN-1 is an inhibitor targeting the oncogenic fusion protein RUNX1-ETO, specifically affecting the NHR2 oligomerization domain. It binds directly to NHR2 (KD,app = 39 µM). By inducing apoptosis and promoting differentiation, RUNX1/ETO-IN-1 exhibits antileukemic activity in RUNX1/ETO translocation acute myeloid leukemia (AML) cells. Its near-neutral charge under physiological pH conditions grants it excellent cell membrane permeability.
Molecular Weight:
399.51
CAS Number:
[923865-06-9]
Formula:
C21H25N3O3S
Target:
Apoptosis|||Others
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