COX-2-IN-55, CAS [[2649115-80-8]] Preis auf Anfrage

Artikelnummer: TGM-T211247
Artikelname: COX-2-IN-55, CAS [[2649115-80-8]] Preis auf Anfrage
Artikelnummer: TGM-T211247
Hersteller Artikelnummer: T211247
Alternativnummer: TGM-T211247-10MG,TGM-T211247-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
COX-2-IN-55 (compound 1) is an orally active Celecoxib analogue with broad-spectrum anticancer properties and relatively weak COX-2 inhibition. It specifically inhibits SERCA2, leading to increased caspase-3 cleavage and DR5 levels, which activates GRP78 and suppresses the progression of triple-negative breast cancer (TNBC). Additionally, COX-2-IN-55 downregulates the angiogenesis markers VEGF-alpha and IL-8, thereby inhibiting microvessel formation.
Molekulargewicht: 486.51
CAS Nummer: [2649115-80-8]
Formel: C24H21F3N4O2S
Target-Kategorie: Calcium Channel|||Caspase|||VEGFR
T211247