COX-2-IN-55, CAS [[2649115-80-8]] Preis auf Anfrage

Catalog Number: TGM-T211247
Article Name: COX-2-IN-55, CAS [[2649115-80-8]] Preis auf Anfrage
Biozol Catalog Number: TGM-T211247
Supplier Catalog Number: T211247
Alternative Catalog Number: TGM-T211247-10MG,TGM-T211247-50MG
Manufacturer: TargetMol
Category: Biochemikalien
COX-2-IN-55 (compound 1) is an orally active Celecoxib analogue with broad-spectrum anticancer properties and relatively weak COX-2 inhibition. It specifically inhibits SERCA2, leading to increased caspase-3 cleavage and DR5 levels, which activates GRP78 and suppresses the progression of triple-negative breast cancer (TNBC). Additionally, COX-2-IN-55 downregulates the angiogenesis markers VEGF-alpha and IL-8, thereby inhibiting microvessel formation.
Molecular Weight: 486.51
CAS Number: [2649115-80-8]
Formula: C24H21F3N4O2S
Target: Calcium Channel|||Caspase|||VEGFR
T211247