COX-2-IN-55, CAS [[2649115-80-8]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T211247
Supplier Catalog Number:
T211247
Alternative Catalog Number:
TGM-T211247-10MG,TGM-T211247-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
COX-2-IN-55 (compound 1) is an orally active Celecoxib analogue with broad-spectrum anticancer properties and relatively weak COX-2 inhibition. It specifically inhibits SERCA2, leading to increased caspase-3 cleavage and DR5 levels, which activates GRP78 and suppresses the progression of triple-negative breast cancer (TNBC). Additionally, COX-2-IN-55 downregulates the angiogenesis markers VEGF-alpha and IL-8, thereby inhibiting microvessel formation.
Molecular Weight:
486.51
CAS Number:
[2649115-80-8]
Formula:
C24H21F3N4O2S
Target:
Calcium Channel|||Caspase|||VEGFR
T211247
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