sEH-IN-21 is an orally active inhibitor of sEH, exhibiting IC50 values of 0.1 nM for both hsEH and msEH. It significantly suppresses the NF-kappaB signaling pathway. sEH-IN-21 demonstrates potent anti-inflammatory activity by reducing IL-6 and TNF-alpha release and maintaining intestinal barrier integrity. It is applicable in research on inflammatory bowel disease (IBD).
Molekulargewicht:
568.73
CAS Nummer:
[3084814-46-7]
Formel:
C30H40N4O5S
Target-Kategorie:
TNF|||Epoxide Hydrolase|||Interleukin|||NF-kappaB
T211654
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
