EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage
Artikelnummer:
TGM-T211961
Hersteller Artikelnummer:
T211961
Alternativnummer:
TGM-T211961-10MG,TGM-T211961-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, with an IC50 of 8 nM determined in the hEP2 SPA assay and an IC50 of 50 nM in the hEP2 cAMP assay. It enhances macrophage-mediated clearance of Amyloid-beta plaques. In CD-1 mice, it shows moderate clearance and good exposure, and exhibits good central nervous system (CNS) exposure in both mice and rats. EP2 receptor antagonist-3 is applicable for research in Alzheimers disease.
Molekulargewicht:
423.87
CAS Nummer:
[1799626-16-6]
Formel:
C23H19ClFN3O2
Target-Kategorie:
Prostaglandin Receptor|||Beta Amyloid
T211961
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