EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage

Product Overview

• Article Name: EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T211961
• Supplier Catalog Number: T211961
• Alternative Catalog Number: TGM-T211961-10MG,TGM-T211961-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, with an IC50 of 8 nM determined in the hEP2 SPA assay and an IC50 of 50 nM in the hEP2 cAMP assay. It enhances macrophage-mediated clearance of Amyloid-beta plaques. In CD-1 mice, it shows moderate clearance and good exposure, and exhibits good central nervous system (CNS) exposure in both mice and rats. EP2 receptor antagonist-3 is applicable for research in Alzheimers disease.

Product Properties

• Molecular Weight: 423.87
• CAS Number: [1799626-16-6]
• Formula: C23H19ClFN3O2
• Target: Prostaglandin Receptor|||Beta Amyloid

Images

T211961